Cardiovascular responses to high-intensity exercise: A systematic literature review comparing trained and untrained individuals

https://doi.org/10.25299/sportarea.2025.vol10(3).21721

Authors

  • Baiq Satrianingsih Department of Physical Education, Faculty of Teacher Training and Education, Universitas Pendidikan Mandalika, Mataram, Nusa Tenggara Barat, Indonesia
  • Risma Department of Physical Education, Faculty of Teacher Training and Education, Universitas Galuh, Ciamis, Jawa Barat, Indonesia https://orcid.org/0000-0002-1753-4266
  • Dupri Department of Physical Education, Faculty of Teacher Training and Education, Universitas Islam Riau, Pekanbaru, Indonesia https://orcid.org/0000-0003-0252-7386
  • Ari Gana Yulianto Department of Sport Education, Postgraduated School, Universitas Pendidikan Indonesia, Bandung, Indonesia/STKIP Darussalam Cilacap, Cilacap, Indonesia

Keywords:

High-intensity interval training, cardiac output, trained individuals, untrained individuals

Abstract

Background: High-intensity exercise induces distinct cardiovascular responses, but systematic comparisons between trained and untrained individuals remain limited. Objective: The primary objective of this study was to compare cardiovascular responses to HIIT specifically heart rate, blood pressure, and blood lactate levels and to identify factors influencing these differences. Methods: A systematic literature review following the PRISMA framework was conducted for this study. The initial search on the Scopus database using keywords such as “High-Intensity Exercise,” “Cardiac Output,” “Trained,” and “Untrained” yielded 380 articles. After a rigorous screening process, which applied strict inclusion and exclusion criteria including the requirement that articles be published in Q1-Q4 ranked journals between 2014 and 2024 a final set of 10 primary articles was selected for in-depth analysis. Findings/Results: High Intensity Interval Training effectively improves cardiovascular function in both trained and untrained individuals. Significant increases in cardiac output and VO₂ max are observed, particularly in trained cyclists. While untrained individuals also benefit, superior cardiovascular adaptations are seen in those who are trained. Furthermore, HIIT is proven to be safe; it does not increase the risk of cardiovascular dysfunction and even has a cardioprotective effect, demonstrated by an increase in cardiac ejection fraction. Conclusion: This review provides the first systematic synthesis comparing cardiovascular responses to high-intensity exercise between trained and untrained individuals. The findings highlight the importance of training status in exercise prescription and offer practical insights for coaches and health practitioners in optimizing high-intensity training programs.

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Author Biographies

Baiq Satrianingsih, Department of Physical Education, Faculty of Teacher Training and Education, Universitas Pendidikan Mandalika, Mataram, Nusa Tenggara Barat, Indonesia

Email: [email protected]

https://orcid.org/0009-0004-4438-1404

mceclip1-6cfbb2d32ee76c823575af8636bc9ce5.png

Risma, Department of Physical Education, Faculty of Teacher Training and Education, Universitas Galuh, Ciamis, Jawa Barat, Indonesia

Email: [email protected]

https://orcid.org/0000-0002-1753-4266

mceclip2-f27dd10252933e9bf6726b12388a246c.png

Dupri, Department of Physical Education, Faculty of Teacher Training and Education, Universitas Islam Riau, Pekanbaru, Indonesia

Email: [email protected]

https://orcid.org/0000-0003-0252-7386

mceclip0-e6d3c22e7ce71298c03777d6fc666633.png

Ari Gana Yulianto, Department of Sport Education, Postgraduated School, Universitas Pendidikan Indonesia, Bandung, Indonesia/STKIP Darussalam Cilacap, Cilacap, Indonesia

Email: [email protected]

https://orcid.org/0000-0002-3430-1632

mceclip1-323693c846fa3128091154ed43dbe85a.png

References

Alekya, B., Goud, K. A., & Chandrasekar, K. A. (2023). A Comparative Study of Cardiovascular Responses to Exercise in Trained and Untrained Individuals. National Journal of Physiology, Pharmacy and Pharmacology, 13(3), 570–573. https://doi.org/10.5455/njppp.2023.13.06299202209082022

Artiluhung, R. R., Mahendra, A., Yulianto, A. G., & Aman, M. S. (2024). Systematic Literature Review: Strategies for Active and Creative Learning in Elementary School Physical Education. ACTIVE: Journal of Physical Education, Sport, Health and Recreation, 13(3), 542–547. https://doi.org/10.15294/peshr.v13i3.13854

Astorino, T. A., Edmunds, R. M., Clark, A., King, L., Gallant, R. M., Namm, S., Fischer, A., & Wood, K. A. (2016). Increased Cardiac Output and Maximal Oxygen Uptake in Response to Ten Sessions of High Intensity Interval Training. The Journal of Sports Medicine and Physical Fitness, 58(1-2), 164–171. https://doi.org/10.23736/S0022-4707.16.06606-8

Atakan, M. M., Li, Y., Koşar, Ş. N., Turnagöl, H. H., & Yan, X. (2021). Evidence-Based Effects of High-Intensity Interval Training on Exercise Capacity and Health: A Review with Historical Perspective. International Journal of Environmental Research and Public Health, 18(13), 7201. https://doi.org/10.3390/ijerph18137201

Bostad, W., Valentino, S. E., McCarthy, D. G., Richards, D. L., MacInnis, M. J., MacDonald, M. J., & Gibala, M. J. (2021). Twelve Weeks of Sprint Interval Training Increases Peak Cardiac Output in Previously Untrained Individuals. European Journal of Applied Physiology, 121(9), 2449–2458. https://doi.org/10.1007/s00421-021-04714-4

Carrick‐Ranson, G., Sloane, N. M., Howden, E. J., Bhella, P. S., Sarma, S., Shibata, S., Fujimoto, N., Hastings, J. L., & Levine, B. D. (2020). The Effect of Lifelong Endurance Exercise on Cardiovascular Structure and Exercise Function in Women. The Journal of Physiology, 598(13), 2589–2605. https://doi.org/10.1113/JP278503

De León Pérez, D., Acosta Vega, R., Salazar Galán, S., Aranda, J. Á., & Francés García, F. (2024). Toward Systematic Literature Reviews in Hydrological Sciences. Water, 16(3), 436. https://doi.org/10.3390/W16030436

Haris, I., Yulianto, A., Ernawati, E., Basrawi, B., & Sari, T. (2024). Correlation Analysis between Physical Literacy, Physical Activity, and Physical Fitness in Students of SMA 1 Kolaka. Journal of Physical and Outdoor Education, 6(2), 41–51. https://doi.org/10.37742/jpoe.v6i2.279

Heber, S., Gleiss, A., Kuzdas‐Sallaberger, M., Hausharter, M., Matousek, M., Ocenasek, H., Fischer, B., Volf, I., & Pokan, R. (2023). Effects of High‐Intensity Interval Training on Trajectories of Gas‐Exchange Measures and Blood Lactate Concentrations during Cardiopulmonary Exercise Tests in Cardiac Rehabilitation—A Randomized Controlled Trial. Scandinavian Journal of Medicine & Science in Sports, 33(8), 1345–1359. https://doi.org/10.1111/sms.14380

Holloway, K., Roche, D., & Angell, P. (2018). Evaluating the Progressive Cardiovascular Health Benefits of Short-Term High-Intensity Interval Training. European Journal of Applied Physiology, 118, 2259–2268. https://doi.org/10.1007/s00421-018-3952-6

Jeremic, N., Weber, G. J., Theilen, N. T., & Tyagi, S. C. (2020). Cardioprotective Effects of High‐Intensity Interval Training are Mediated Through Microrna Regulation of Mitochondrial and Oxidative Stress Pathways. Journal of Cellular Physiology, 235(6), 5229–5240. https://doi.org/10.1002/jcp.29409

Karlsen, T., Aamot, I.-L., Haykowsky, M., & Rognmo, Ø. (2017). High Intensity Interval Training for Maximizing Health Outcomes. Progress in Cardiovascular Diseases, 60(1), 67–77. https://doi.org/10.1016/j.pcad.2017.03.006

Kim, H., Sefcik, J. S., & Bradway, C. (2017). Characteristics of qualitative descriptive studies: A systematic review. Research in Nursing & Health, 40(1), 23–42. https://doi.org/10.1002/nur.21768

Kitchenham, B., Pretorius, R., Budgen, D., Brereton, O. P., Turner, M., Niazi, M., & Linkman, S. (2010). Systematic Literature Reviews in Software Engineering–A Tertiary Study. Information and Software Technology, 52(8), 792–805. https://doi.org/10.1016/j.infsof.2010.03.006

Ksoll, K. S. H., Mühlberger, A., & Stöcker, F. (2021). Central and Peripheral Oxygen Distribution in Two Different Modes of Interval Training. Metabolites, 11(11), 790. https://doi.org/10.3390/metabo11110790

Langeard, A., Cloutier, S.-O., Olmand, M., Saillant, K., Gagnon, C., Grégoire, C.-A., Fortier, A., Lacroix, M., Lalongé, J., & Gayda, M. (2021). High-Intensity Interval Training vs. Hydrochlorothiazide on Blood Pressure, Cardiovascular Health and Cognition: Protocol of a Non-Inferiority Trial. Contemporary Clinical Trials, 102, 106286. https://doi.org/10.1016/j.cct.2021.106286

Luo, X., Zhang, D., & Yu, W. (2024). Uniform Homeostatic Stress Through Individualized Interval Training Facilitates Homogeneous Adaptations Across Rowers with Different Profiles. International Journal of Sports Physiology and Performance, 19(3), 232–241. https://doi.org/10.1123/ijspp.2023-0246

McCafferty, P., & Mercado Garcia, E. (2024). Systematic Bibliographic Database Searching for an Overview of Reviews: A Practical Guide Using Children’s Participation as a Case Study. The British Journal of Social Work, 54(3), 1033–1052. https://doi.org/10.1093/BJSW/BCAE008

Moher, D., Liberati, A., Tetzlaff, J., Altman, D. G., & Group, P. (2010). Preferred Reporting Items for Systematic Reviews and Meta-Analyses: The PRISMA Statement. International Journal of Surgery, 8(5), 336–341. https://doi.org/10.1016/j.ijsu.2010.02.007

Permana, G., Carsiwan, C., Juliantine, T., Yulianto, A. G., Aman, M. S., & Shahudin, N. N. (2024). The Contribution of Physical Education Teachers in Shaping Student Character. ACTIVE: Journal of Physical Education, Sport, Health and Recreation, 13(3), 552–556. https://doi.org/10.15294/peshr.v13i3.14059

Plizga, J., Jaworski, A., Grajnert, F., Gluszczyk, A., Surma, A., Cecot, J., Parfianowicz, A., Zarzecki, K., Mandryk, M., & Holdun, N. (2024). High-Intensity Interval Training-Health Benefits and Risks-Literature Review. Quality in Sport, 18, 53359. https://doi.org/10.12775/QS.2024.18.53359

Pozo, P., Grao-Cruces, A., & Pérez-Ordás, R. (2018). Teaching Personal and Social Responsibility Model-Based Programmes in Physical Education: A Systematic Review. European Physical Education Review, 24(1), 56–75. https://doi.org/10.1177/1356336X16664749

Saugel, B., Kouz, K., Scheeren, T. W. L., Greiwe, G., Hoppe, P., Romagnoli, S., & de Backer, D. (2021). Cardiac Output Estimation Using Pulse Wave Analysis—Physiology, Algorithms, and Technologies: A Narrative Review. British Journal of Anaesthesia, 126(1), 67–76. https://doi.org/10.1016/j.bja.2020.09.049

Spee, R. F., Niemeijer, V. M., Schoots, T., Tuinenburg, A., Houthuizen, P., Wijn, P. F., Doevendans, P. A., & Kemps, H. M. (2020). High Intensity Interval Training after Cardiac Resynchronization Therapy: An Explorative Randomized Controlled Trial. International Journal of Cardiology, 299, 169–174. https://doi.org/10.1016/j.ijcard.2019.07.023

Strasser, B., & Burtscher, M. (2018). Survival of the Fittest: VO2max, A Key Predictor of Longevity. Front Biosci (Landmark Ed), 23(8), 1505–1516. https://doi.org/10.2741/4657

Tangchaisuriya, P., Chuensiri, N., Tanaka, H., & Suksom, D. (2021). Physiological Adaptations to High-Intensity Interval Training Combined with Blood Flow Restriction in Masters Road Cyclists. Medicine and Science in Sports and Exercise, 54(5), 830–840. https://doi.org/10.1249/MSS.0000000000002857

Wahl, P., Bloch, W., & Proschinger, S. (2022). The Molecular Signature of High-Intensity Training in the Human Body. International Journal of Sports Medicine, 43(03), 195–205. https://doi.org/10.1055/a-1551-9294

Wiewelhove, T., Raeder, C., Meyer, T., Kellmann, M., Pfeiffer, M., & Ferrauti, A. (2015). Markers for Routine Assessment of Fatigue and Recovery in Male and Female Team Sport Athletes during High-Intensity Interval Training. PloS One, 10(10), e0139801. https://doi.org/10.1371/journal.pone.0139801

Xin, C., Fu, J., Zhou, Z., Zhou, Y., & He, H. (2024). Effects of Aquatic and Land High Intensity Interval Training on Hemodynamics and Vascular Function of Middle-Aged Men. Frontiers in Physiology, 15, 1411277. https://doi.org/10.3389/fphys.2024.1411277

Yulianto, A. G., Satrianingsih, B., & Faridah, A. (2024). Ekstrakurikuler sebagai Wahana: Strategi Efektif Mengembangkan Life Skills Siswa. Journal Olympic (Physical Education, Health and Sport), 4(2), 103–110. https://doi.org/10.36709/jolympic.v4i2.119

Published

2025-11-19

How to Cite

Satrianingsih, B., Risma, Dupri, & Yulianto, A. G. (2025). Cardiovascular responses to high-intensity exercise: A systematic literature review comparing trained and untrained individuals. Journal Sport Area, 10(3), 323–340. https://doi.org/10.25299/sportarea.2025.vol10(3).21721

Issue

Section

REVIEW ARTICLES
Received 2025-03-15
Accepted 2025-08-22
Published 2025-11-19